Surface functionalized nanoparticles of NVP an improved strategy to tackle deadly HIV infection
نویسندگان
چکیده
Results GMS nVP auNPs with > 75% entrapment efficiency & < 300nm particle size were prepared and surface modified nanoparticles showed >85% binding to the ligand. In cytotoxicity study nanoformulations showed higher cell viability at all time points as compared to NVP. Cell uptake study revealed higher uptake of nanoparticles as compared to NVP only. In vitro anti HIV assay of surface modified revealed 10 fold increased activity as compared to NVP.
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